Injectable polydimethylsiloxane-hydroxyapatite composite cement
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An injectable polydimethylsiloxane/hydroxyapatite (PDMS/HAp) composite cement was synthesised using linear PDMS and HAp (particles of about 100 nm in size) of different mass fractions. The effect of HAp mass fraction (5-60 mass%) on the hardness of PDMS/HAp composite cement was investigated. The hardness achieved is 25-49degreesShA. Differential scanning calorimetry (DSC) was used to study the cross-linking process and the influence of HAp on the temperature and duration of PDMS/HAp cross-linking. The microstructure of composite cement surfaces after 10 days in vivo tests was observed by scanning electron microscopy (SEM). The presence of well-adhered macrophages, fibroblasts and monocytes was found on the implant surface upon its extraction from the organism.
Кључне речи:composite cement / polydimethylsiloxane/hydroxyapatite / hardness / cross-linking / in vivo test
Извор:Bio-medical Materials and Engineering, 2003, 13, 4, 401-410
ISSN: 0959-2989 (print)