Optofluidic Micromachined Platform for Refractive Index Measurement
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We present a combination of micromachined optofluidic platforms equipped with a fiber-optic sensing configuration based on a three-path Mach–Zehnder interferometer (MZI) for simultaneous measurement of the refractive index of liquids and the autocalibration in dynamic regime. The sensing principle is based on the low-coherence interferometry, characterized by a generation of Gaussian enveloped interferograms, for which the position of its maximum depends on the optical path difference (OPD) between the sensing and reference arm of the MZI. When liquid flows through the central microchannel of the optofluidic platform it crosses the light beam between the two optical fibers in the sensing arm causing the OPD change. An algorithm has been applied for the calculation of the refractive index of liquids out of the raw interference signals. We obtained a very good agreement between the experimental results and literature data of refractive indices of subjected fluids. The accuracy of refract...ive index measurement is approximately 1%, predominantly determined by the accuracy of reading the position of the mechanical scanner. The proposed sensor is attractive for the label-free biological, biochemical, and chemical sensing owing autocalibration and high sensitivity yet consuming a very small sample volume of 1 µL. It is capable to measure the refractive index of various liquids and/or gases simultaneously in the process.
Кључне речи:
fiber-optic sensors / refractive index / interferometry / optofluidic / micromachiningИзвор:
Chemosensors, 2022, 10, 5, 197-Издавач:
- MDPI AG
Финансирање / пројекти:
- NFB and ACMIT Gmbh, Austria: LSC15-004 project “Immune-regulatory capacity of mesenchymal stem cells (MSCs)
- Министарство науке, технолошког развоја и иновација Републике Србије, институционално финансирање - 200175 (Институт техничких наука САНУ, Београд) (RS-MESTD-inst-2020-200175)
DOI: 10.3390/chemosensors10050197
ISSN: 2227-9040
WoS: 00080250720000
Scopus: 2-s2.0-85135226517
Институција/група
Институт техничких наука САНУ / Institute of Technical Sciences of SASATY - JOUR AU - Đinović, Zoran AU - Tomić, Miloš AU - Kocsis, Agnes PY - 2022 UR - https://dais.sanu.ac.rs/123456789/13157 AB - We present a combination of micromachined optofluidic platforms equipped with a fiber-optic sensing configuration based on a three-path Mach–Zehnder interferometer (MZI) for simultaneous measurement of the refractive index of liquids and the autocalibration in dynamic regime. The sensing principle is based on the low-coherence interferometry, characterized by a generation of Gaussian enveloped interferograms, for which the position of its maximum depends on the optical path difference (OPD) between the sensing and reference arm of the MZI. When liquid flows through the central microchannel of the optofluidic platform it crosses the light beam between the two optical fibers in the sensing arm causing the OPD change. An algorithm has been applied for the calculation of the refractive index of liquids out of the raw interference signals. We obtained a very good agreement between the experimental results and literature data of refractive indices of subjected fluids. The accuracy of refractive index measurement is approximately 1%, predominantly determined by the accuracy of reading the position of the mechanical scanner. The proposed sensor is attractive for the label-free biological, biochemical, and chemical sensing owing autocalibration and high sensitivity yet consuming a very small sample volume of 1 µL. It is capable to measure the refractive index of various liquids and/or gases simultaneously in the process. PB - MDPI AG T2 - Chemosensors T1 - Optofluidic Micromachined Platform for Refractive Index Measurement SP - 197 VL - 10 IS - 5 DO - 10.3390/chemosensors10050197 UR - https://hdl.handle.net/21.15107/rcub_dais_13157 ER -
@article{ author = "Đinović, Zoran and Tomić, Miloš and Kocsis, Agnes", year = "2022", abstract = "We present a combination of micromachined optofluidic platforms equipped with a fiber-optic sensing configuration based on a three-path Mach–Zehnder interferometer (MZI) for simultaneous measurement of the refractive index of liquids and the autocalibration in dynamic regime. The sensing principle is based on the low-coherence interferometry, characterized by a generation of Gaussian enveloped interferograms, for which the position of its maximum depends on the optical path difference (OPD) between the sensing and reference arm of the MZI. When liquid flows through the central microchannel of the optofluidic platform it crosses the light beam between the two optical fibers in the sensing arm causing the OPD change. An algorithm has been applied for the calculation of the refractive index of liquids out of the raw interference signals. We obtained a very good agreement between the experimental results and literature data of refractive indices of subjected fluids. The accuracy of refractive index measurement is approximately 1%, predominantly determined by the accuracy of reading the position of the mechanical scanner. The proposed sensor is attractive for the label-free biological, biochemical, and chemical sensing owing autocalibration and high sensitivity yet consuming a very small sample volume of 1 µL. It is capable to measure the refractive index of various liquids and/or gases simultaneously in the process.", publisher = "MDPI AG", journal = "Chemosensors", title = "Optofluidic Micromachined Platform for Refractive Index Measurement", pages = "197", volume = "10", number = "5", doi = "10.3390/chemosensors10050197", url = "https://hdl.handle.net/21.15107/rcub_dais_13157" }
Đinović, Z., Tomić, M.,& Kocsis, A.. (2022). Optofluidic Micromachined Platform for Refractive Index Measurement. in Chemosensors MDPI AG., 10(5), 197. https://doi.org/10.3390/chemosensors10050197 https://hdl.handle.net/21.15107/rcub_dais_13157
Đinović Z, Tomić M, Kocsis A. Optofluidic Micromachined Platform for Refractive Index Measurement. in Chemosensors. 2022;10(5):197. doi:10.3390/chemosensors10050197 https://hdl.handle.net/21.15107/rcub_dais_13157 .
Đinović, Zoran, Tomić, Miloš, Kocsis, Agnes, "Optofluidic Micromachined Platform for Refractive Index Measurement" in Chemosensors, 10, no. 5 (2022):197, https://doi.org/10.3390/chemosensors10050197 ., https://hdl.handle.net/21.15107/rcub_dais_13157 .