• Bioactive composite materials in regeneration of the resorbed bone of alveolar ridges 

      Ajduković, Zorica; Ignjatović, Nenad; Rajković, Jelena; Najman, Stevo; Mihailović, Dragan; Petrović, D.; Kenić Marinković, Dragana; Uskoković, Dragan (Belgrade : Materials Research Society of Serbia; Institute of Technical Sciences of SASA; Vinča Institute of Nuclear Sciences, University of Belgrade, 2012)
      Bone loss during the systemic osteoporosis has an important role in dentistry and medicine. The aim of the study was the application of bioactive micro and nanocomposite materials, alone, and in combination with autologous ...
    • Biomaterials and their application in preprosthetic surgical procedure 

      Ajduković, Zorica; Đorđević, Nadica; Petrović, Nenad; Ignjatović, Nenad; Kenić Marinković, Dragana; Uskoković, Dragan (Belgrade : Institute of Technical Sciences of SASA, 2013)
      The loss of teeth and damage to the jaw bone occur under different circumstances. The deficit may be the result of wearing inadequate dentures, residual ridge resorption, osteoporosis, periodontal disease, trauma, tumors, ...
    • Chitosan-PLGA polymer blends as coatings for hydroxyapatite nanoparticles and their effect on antimicrobial properties, osteoconductivity and regeneration of osseous tissues 

      Ignjatović, Nenad; Wu, Victoria; Ajduković, Zorica; Mihajilov Krstev, Tatjana; Uskoković, Vuk; Uskoković, Dragan (Elsevier, 2016)
      Composite biomaterials comprising nanostructured hydroxyapatite (HAp) have an enormous potential for natural bone tissue reparation, filling and augmentation. Chitosan (Ch) as a naturally derived polymer has many physicochemical ...
    • Chitosan-PLGA polymer blends as coatings for hydroxyapatite nanoparticles and their effect on antimicrobial properties, osteoconductivity and regeneration of osseous tissues 

      Ignjatović, Nenad; Wu, Victoria; Ajduković, Zorica; Mihajilov Krstev, Tatjana; Uskoković, Vuk; Uskoković, Dragan (Materials science & engineering. C, Materials for biological applications, 2016)
      Composite biomaterials comprising nanostructured hydroxyapatite (HAp) have an enormous potential for natural bone tissue reparation, filling and augmentation. Chitosan (Ch) as a naturally derived polymer has many physicochemical ...
    • Comparative study of the effects of different nanomaterials on the viability of human osteoblast-like cells 

      Stojanović, S.; Najman, Stevo; Ajduković, Zorica; Ignjatović, Nenad; Uskoković, Dragan (Belgrade : Materials Research Society of Serbia, 2012)
      The aim of this study was to compare the effects of two types of nanomaterials, cobalt-exchanged hydroxyapatite (CoHAp) and calcium phosphate/poly-(DL-lactide-co-glycolide) (CP/PLGA), on the viability of Saos-2 osteoblast-like ...
    • Enhanced Osteogenesis of Nanosized Cobalt-substituted Hydroxyapatite 

      Ignjatović, Nenad; Ajduković, Zorica; Rajković, Jelena; Najman, Stevo; Mihailović, Dragan; Uskoković, Dragan (Elsevier, 2015)
      Hydroxyapatite (HAp) is an extensively studied material with known biocompatible and osteoconductive properties in bone tissue reconstruction. The improvement of the osteogenetic potential of HAp has been tested through ...
    • Evaluation compensation of an osteoporotic rat bone with Ca/Co-HAp nanoparticles 

      Ajduković, Zorica; Petrović, Milica B.; Milićević, Jelena; Đorđević, Nadica; Ignjatović, Nenad; Uskoković, Dragan; Savić, Vojin P. (Belgrade : Institute of Technical Sciences of SASA, 2010)
      This study examined the role of Ca / Co-HAp nanoparticles on time distance in regeneration of osteoporotic alveolar bone in rats by biochemical blood markers analysis (ALP, Ca, Mg, P) and through histochemical analysis. ...
    • Examination of the influence of nanomaterials calcium phosphate/poly(DL-lactide-co-glycolide) and cobalt-exchanged hydroxyapatite on the viability of Saos-2 cells 

      Najman, Stevo; Stojanović, Sanja; Mitrić, Žarko; Ajduković, Zorica; Ignjatović, Nenad; Uskoković, Dragan (Belgrade : Materials Research Society of Serbia; Institute of Technical Sciences of SASA; Vinča Institute of Nuclear Sciences, University of Belgrade, 2012)
      We have examined the effect of extracts of the calcium phosphate/poly(DL-lactide-co-glycolide) (CP/PLGA) and cobalt-exchanged hydroxyapatite (CoHAp), on the viability of Saos2 osteoblastlike cells. Extracts were prepared ...
    • Hemolytic activity of bioactive nanocomposites 

      Ajduković, Zorica; Ignjatović, Nenad; Petrović, N.; Najman, Stevo; Rajković, J.; Kenić Marinković, Dragana; Krstić, V.; Uskoković, Dragan (Belgrade : Materials Research Society of Serbia; Institute of Technical Sciences of SASA; Vinča Institute of Nuclear Sciences, University of Belgrade, 2012)
      Huge range of tested biomaterials in recent decades has emerged as an ideal scaffold for cell growth, but few have demonstrated clinical efficacy. Among them, synthetic hydroxyapatite (HAp, Ca10(PO4)6(OH)2) is the most ...
    • Histochemical observation and the analysis of biochemical bone regeneration markers in treatment of an osteoporotic rat bone with Ca/Co-HAp nanoparticles 

      Ajduković, Zorica; Petrović, Milica B.; Milićević, Jelena; Đorđević, N.; Ignjatović, Nenad; Uskoković, Dragan; Savić, Vojin (Belgrade : Institute of Technical Sciences of SASA, 2010)
      One of the prerequisites for a good prosthetic rehabilitation is well preserved bone tissue. However, osteoporosis as a modern age disease often compromises a good dental treatment. Oral implantology offers a solution ...
    • Hydroxyapatite and hydroxyapatite substituents in strengthening of the jaw bone tegmenta 

      Ajduković, Zorica; Ignjatović, Nenad; Savić, Vojin; Najman, Stevo; Mihailović, Dragan; Rajković, J.; Petrović, N.; Uskoković, Dragan (Belgrade : Materials Research Society of Serbia, 2012)
      In recent years, calcium hydroxyapatite (HAp) and its substituents are increasingly used in dentistry and medicine. The influence of nanoparticles Ca / Co-HAp in strengthening weak osteoporotic bone jaw tegmenta was tested ...
    • In vitro evaluation of antimicrobial activity of nano composite biomaterials based on hydroxyapatite 

      Ajduković, Zorica; Milićević, Jelena; Petrović, Milica B.; Đorđević, Nadica; Mladenović Antić, Snežana; Kocić, Branislava; Ignjatović, Nenad; Uskoković, Dragan; Savić, Vojin P. (Belgrade : Institute of Technical Sciences of SASA, 2010)
      Antimicrobial materials based on hydroxyapatite are potentially attractive in a wide variety of medical and stomatological applications. The objective of this paper is to examine antimicrobic activity of cobalt-substituted ...
    • In Vitro Evaluation of Nanoscale Hydroxyapatite-Based Bone Reconstructive Materials with Antimicrobial Properties 

      Ajduković, Zorica; Mihajilov Krstev, Tatjana; Ignjatović, Nenad; Stojanović, Zoran S.; Mladenović Antić, Snežana; Kocić, Branislava; Najman, Stevo; Petrović, Nenad D.; Uskoković, Dragan (American Scientific Publishers, 2016)
      In the field of oral implantology the loss of bone tissue prevents adequate patient care, and calls for the use of synthetic biomaterials with properties that resemble natural bone. Special attention is paid to the risk ...
    • Interaction of nanoparticles and biological fluids 

      Ajduković, Zorica; Ignjatović, Nenad; Petrović, Nenad; Rajković, Jelena; Kenić Marinković, Dragana; Najman, Stevo; Mihailović, Dragan; Uskoković, Dragan (Belgrade : Materials Research Society of Serbia, 2014)
      Recent studies have shown that the behavior of nanoparticles in in vivo conditions is not solely dependant on their physical properties, such are size and shape. The surface of nanoparticles in biological fluids interacts ...
    • Joint effects of vitamin D and nanobiomaterial in the jaw bone regeneration 

      Ajduković, Zorica; Ignjatović, Nenad; Petrović, Nenad; Savić, Vojin; Mihailović, Dragan; Uskoković, Dragan (Belgrade : Institute of Technical Sciences of the Serbian Academy of Sciences and Arts, 2011)
      Systems for targeted delivery of drugs with high affinity for specific organs, tissues, and cells were introduced at the beginning of the twentieth century. Recently, this concept is attracting much attention. These systems ...
    • Mineral substances in the bone tissue and blood of patients with osteoporosis 

      Ajduković, Zorica; Dimić, A.; Stanković, S.; Krunić, N.; Aleksov, L.; Ignjatović, Nenad (Novi Sad : Društvo lekara Vojvodine Srpskog lekarskog društva, 2009)
      INTRODUCTION: Osteoporosis is a very common disorder of skeleton, which can be caused by various metabolic disturbances, malnutrition, immobilization, endocrine disorders, bone marrow diseases, connective tissue disorders, ...
    • Multifunctional hydroxyapatite and poly(D,L-lactide-co-glycolide) nanoparticles for the local delivery of cholecalciferol 

      Ignjatović, Nenad; Uskoković, Vuk; Ajduković, Zorica; Uskoković, Dragan (Materials Science and Engineering: C, 2013)
      Cholecalciferol, vitamin D3, plays an important role in bone metabolism by regulating extracellular levels of calcium. Presented here is a study on the effects of the local delivery of cholecalciferol (D3) using nanoparticulate ...
    • Multifunctional hydroxyapatite and poly(D,L-lactide-co-glycolide) nanoparticles for the local delivery of cholecalciferol 

      Ignjatović, Nenad; Uskoković, Vuk; Ajduković, Zorica; Uskoković, Dragan (Elsevier, 2013)
      Cholecalciferol, vitamin D3, plays an important role in bone metabolism by regulating extracellular levels of calcium. Presented here is a study on the effects of the local delivery of cholecalciferol (D3) using nanoparticulate ...
    • Multifunctional nano particulate systems based on hydroxyapatite as systems for local delivery of vitamin D3 

      Ignjatović, Nenad; Ajduković, Zorica; Drmanić, Saša Ž.; Uskoković, Dragan (Belgrade : Materials Research Society of Serbia, 2011)
      Multifunctional drug delivery system based on hydroxyapatite may be a research challenge in the treatment and reconstruction of bone tissue. Vitamin D3 has a positive effect on osteogenesis as it increases osteoblast ...
    • Multifunctional nano scale drug delivery particles based on vitamin D3-loaded hydroxyapatite in bone tissue engineering 

      Ignjatović, Nenad; Ajduković, Zorica; Uskoković, Vuk; Uskoković, Dragan (Belgrade : Materials Research Society of Serbia, 2012)
      Specific group of controlled drug delivery systems in bone tissue engineering are multifunctional nanoparticle systems (MNPs) based on hydroxyapatite coated with drug loadedbioresorbable polymer. This study illustrates the ...