TY  - JOUR
AU  - Krueger, Eddy
AU  - Popović-Maneski, Lana
AU  - Neto, Guilherme Nunes Nogueira
AU  - Mendonça Scheeren, Eduardo
AU  - Fiusa, Jessika Mehret
AU  - Nohama, Percy
PY  - 2020
UR  - https://doi.org/10.1007/s42600-020-00061-z
UR  - https://dais.sanu.ac.rs/123456789/9817
AB  - Functional electrical stimulation (FES) is a method of activating paralyzed muscles. During FES application, fast muscle fatigue can occur (the inability of stimulated muscles to generate force). Therefore, it is beneficial to estimate the muscle fatigue for FES closed-loop control for walking to prevent unexpected muscle collapse and adapt the FES strategy in real time. Mechanomyography (MMG) is a noninvasive technique for registering myofiber vibrations, representing an ideal candidate for the provision of feedback. The hypothesis was that MMG signals could effectively detect muscle fatigue and, thus, provide feedback.
PB  - Springer
T2  - Research on Biomedical Engineering
T1  - Neuromuscular fatigue detection by mechanomyography in people with complete spinal cord injury
SP  - 203
EP  - 212
VL  - 36
IS  - 3
DO  - 10.1007/s42600-020-00061-z
UR  - https://hdl.handle.net/21.15107/rcub_dais_9817
ER  - 

@article{
author = "Krueger, Eddy and Popović-Maneski, Lana and Neto, Guilherme Nunes Nogueira and Mendonça Scheeren, Eduardo and Fiusa, Jessika Mehret and Nohama, Percy",
year = "2020",
abstract = "Functional electrical stimulation (FES) is a method of activating paralyzed muscles. During FES application, fast muscle fatigue can occur (the inability of stimulated muscles to generate force). Therefore, it is beneficial to estimate the muscle fatigue for FES closed-loop control for walking to prevent unexpected muscle collapse and adapt the FES strategy in real time. Mechanomyography (MMG) is a noninvasive technique for registering myofiber vibrations, representing an ideal candidate for the provision of feedback. The hypothesis was that MMG signals could effectively detect muscle fatigue and, thus, provide feedback.",
publisher = "Springer",
journal = "Research on Biomedical Engineering",
title = "Neuromuscular fatigue detection by mechanomyography in people with complete spinal cord injury",
pages = "203-212",
volume = "36",
number = "3",
doi = "10.1007/s42600-020-00061-z",
url = "https://hdl.handle.net/21.15107/rcub_dais_9817"
}

Krueger, E., Popović-Maneski, L., Neto, G. N. N., Mendonça Scheeren, E., Fiusa, J. M.,& Nohama, P.. (2020). Neuromuscular fatigue detection by mechanomyography in people with complete spinal cord injury. in Research on Biomedical Engineering
Springer., 36(3), 203-212.
https://doi.org/10.1007/s42600-020-00061-z
https://hdl.handle.net/21.15107/rcub_dais_9817

Krueger E, Popović-Maneski L, Neto GNN, Mendonça Scheeren E, Fiusa JM, Nohama P. Neuromuscular fatigue detection by mechanomyography in people with complete spinal cord injury. in Research on Biomedical Engineering. 2020;36(3):203-212.
doi:10.1007/s42600-020-00061-z
https://hdl.handle.net/21.15107/rcub_dais_9817 .

Krueger, Eddy, Popović-Maneski, Lana, Neto, Guilherme Nunes Nogueira, Mendonça Scheeren, Eduardo, Fiusa, Jessika Mehret, Nohama, Percy, "Neuromuscular fatigue detection by mechanomyography in people with complete spinal cord injury" in Research on Biomedical Engineering, 36, no. 3 (2020):203-212,
https://doi.org/10.1007/s42600-020-00061-z .,
https://hdl.handle.net/21.15107/rcub_dais_9817 .

TY  - JOUR
AU  - Krueger, Eddy
AU  - Magri, L. M. S.
AU  - Botelho, A. S.
AU  - Bach, F. S.
AU  - Rebellato, C. L. K.
AU  - Fracaro, L.
AU  - Fragoso, F. Y. I.
AU  - Villanova, J. A.
AU  - Brofman, P. R. S.
AU  - Popović Maneski, Lana
PY  - 2019
UR  - http://www.sciencedirect.com/science/article/pii/S0304394018308498
UR  - https://dais.sanu.ac.rs/123456789/4596
AB  - The application of low-intensity electrical stimulation (LIES) to neural tissue increases neurochemical factors responsible for regeneration as nerve growth factor. Stem cell (SC) therapy for patients with Spinal cord injury (SCI) promote some increase functional improvement.ObjectiveInvestigate the electromyographic response in paraplegic dogs undergoing LIES and SC transplantation.Methods27 dogs paraplegics with SCI were divided into three groups with different types of therapy. GADSC: two SC transplants (n = 9); GLIES: LIES (n = 8); GCOMB: two SC transplants and LIES (n = 10). Adipose derived mesenchymal stem cells (ADSCs) were transplanted by lumbar puncture in the amount of 1.2 × 106 cells/50 μL. Acupuncture needles positioned in the interspinous space were used for stimulation. The electrical stimulation was applied with a mean voltage ∼30 mV and four consecutive modulated frequencies (5 Hz, 10 Hz, 15 Hz and 20 Hz) within 5 min each. The patients motor performance was evaluated before (Pre) the procedure and after 30 (Post30) and 60 (Post60) days, from electromyography root mean square (EMGRMS) registered with subcutaneous electrodes in the vastus lateralis muscle, while the animals were in quadrupedal position.ResultsAll three groups showed a significant intra-group increase of EMGRMS (Pre vs. Post30 or Pre vs. Post60). However, there were no statistically significant differences between Post30 and Post60. The inter-group test (GADSC X GLIES X GCOMB) did not present significance when compared the instants Pre (p = 0.34), Post30 (p = 0.78) and Post60 (p = 0.64).ConclusionSome dogs recovered motor activity, expressed by the EMGRMS, in all groups, in pre vs. post (30 or 60 days) comparisons.
PB  - Elsevier
T2  - Neuroscience Letters
T1  - Effects of low-intensity electrical stimulation and adipose derived stem cells transplantation on the time-domain analysis-based electromyographic signals in dogs with SCI
SP  - 38
EP  - 45
VL  - 696
DO  - 10.1016/j.neulet.2018.12.004
UR  - https://hdl.handle.net/21.15107/rcub_dais_4596
ER  - 

@article{
author = "Krueger, Eddy and Magri, L. M. S. and Botelho, A. S. and Bach, F. S. and Rebellato, C. L. K. and Fracaro, L. and Fragoso, F. Y. I. and Villanova, J. A. and Brofman, P. R. S. and Popović Maneski, Lana",
year = "2019",
abstract = "The application of low-intensity electrical stimulation (LIES) to neural tissue increases neurochemical factors responsible for regeneration as nerve growth factor. Stem cell (SC) therapy for patients with Spinal cord injury (SCI) promote some increase functional improvement.ObjectiveInvestigate the electromyographic response in paraplegic dogs undergoing LIES and SC transplantation.Methods27 dogs paraplegics with SCI were divided into three groups with different types of therapy. GADSC: two SC transplants (n = 9); GLIES: LIES (n = 8); GCOMB: two SC transplants and LIES (n = 10). Adipose derived mesenchymal stem cells (ADSCs) were transplanted by lumbar puncture in the amount of 1.2 × 106 cells/50 μL. Acupuncture needles positioned in the interspinous space were used for stimulation. The electrical stimulation was applied with a mean voltage ∼30 mV and four consecutive modulated frequencies (5 Hz, 10 Hz, 15 Hz and 20 Hz) within 5 min each. The patients motor performance was evaluated before (Pre) the procedure and after 30 (Post30) and 60 (Post60) days, from electromyography root mean square (EMGRMS) registered with subcutaneous electrodes in the vastus lateralis muscle, while the animals were in quadrupedal position.ResultsAll three groups showed a significant intra-group increase of EMGRMS (Pre vs. Post30 or Pre vs. Post60). However, there were no statistically significant differences between Post30 and Post60. The inter-group test (GADSC X GLIES X GCOMB) did not present significance when compared the instants Pre (p = 0.34), Post30 (p = 0.78) and Post60 (p = 0.64).ConclusionSome dogs recovered motor activity, expressed by the EMGRMS, in all groups, in pre vs. post (30 or 60 days) comparisons.",
publisher = "Elsevier",
journal = "Neuroscience Letters",
title = "Effects of low-intensity electrical stimulation and adipose derived stem cells transplantation on the time-domain analysis-based electromyographic signals in dogs with SCI",
pages = "38-45",
volume = "696",
doi = "10.1016/j.neulet.2018.12.004",
url = "https://hdl.handle.net/21.15107/rcub_dais_4596"
}

Krueger, E., Magri, L. M. S., Botelho, A. S., Bach, F. S., Rebellato, C. L. K., Fracaro, L., Fragoso, F. Y. I., Villanova, J. A., Brofman, P. R. S.,& Popović Maneski, L.. (2019). Effects of low-intensity electrical stimulation and adipose derived stem cells transplantation on the time-domain analysis-based electromyographic signals in dogs with SCI. in Neuroscience Letters
Elsevier., 696, 38-45.
https://doi.org/10.1016/j.neulet.2018.12.004
https://hdl.handle.net/21.15107/rcub_dais_4596

Krueger E, Magri LMS, Botelho AS, Bach FS, Rebellato CLK, Fracaro L, Fragoso FYI, Villanova JA, Brofman PRS, Popović Maneski L. Effects of low-intensity electrical stimulation and adipose derived stem cells transplantation on the time-domain analysis-based electromyographic signals in dogs with SCI. in Neuroscience Letters. 2019;696:38-45.
doi:10.1016/j.neulet.2018.12.004
https://hdl.handle.net/21.15107/rcub_dais_4596 .

Krueger, Eddy, Magri, L. M. S., Botelho, A. S., Bach, F. S., Rebellato, C. L. K., Fracaro, L., Fragoso, F. Y. I., Villanova, J. A., Brofman, P. R. S., Popović Maneski, Lana, "Effects of low-intensity electrical stimulation and adipose derived stem cells transplantation on the time-domain analysis-based electromyographic signals in dogs with SCI" in Neuroscience Letters, 696 (2019):38-45,
https://doi.org/10.1016/j.neulet.2018.12.004 .,
https://hdl.handle.net/21.15107/rcub_dais_4596 .

TY  - JOUR
AU  - Krueger, Eddy
AU  - Magri, L. M. S.
AU  - Botelho, A. S.
AU  - Bach, F. S.
AU  - Rebellato, C. L. K.
AU  - Fracaro, L.
AU  - Fragoso, F. Y. I.
AU  - Villanova, J. A.
AU  - Brofman, P. R. S.
AU  - Popović Maneski, Lana
PY  - 2019
UR  - http://www.sciencedirect.com/science/article/pii/S0304394018308498
UR  - https://dais.sanu.ac.rs/123456789/4595
AB  - The application of low-intensity electrical stimulation (LIES) to neural tissue increases neurochemical factors responsible for regeneration as nerve growth factor. Stem cell (SC) therapy for patients with Spinal cord injury (SCI) promote some increase functional improvement.ObjectiveInvestigate the electromyographic response in paraplegic dogs undergoing LIES and SC transplantation.Methods27 dogs paraplegics with SCI were divided into three groups with different types of therapy. GADSC: two SC transplants (n = 9); GLIES: LIES (n = 8); GCOMB: two SC transplants and LIES (n = 10). Adipose derived mesenchymal stem cells (ADSCs) were transplanted by lumbar puncture in the amount of 1.2 × 106 cells/50 μL. Acupuncture needles positioned in the interspinous space were used for stimulation. The electrical stimulation was applied with a mean voltage ∼30 mV and four consecutive modulated frequencies (5 Hz, 10 Hz, 15 Hz and 20 Hz) within 5 min each. The patients motor performance was evaluated before (Pre) the procedure and after 30 (Post30) and 60 (Post60) days, from electromyography root mean square (EMGRMS) registered with subcutaneous electrodes in the vastus lateralis muscle, while the animals were in quadrupedal position.ResultsAll three groups showed a significant intra-group increase of EMGRMS (Pre vs. Post30 or Pre vs. Post60). However, there were no statistically significant differences between Post30 and Post60. The inter-group test (GADSC X GLIES X GCOMB) did not present significance when compared the instants Pre (p = 0.34), Post30 (p = 0.78) and Post60 (p = 0.64).ConclusionSome dogs recovered motor activity, expressed by the EMGRMS, in all groups, in pre vs. post (30 or 60 days) comparisons.
PB  - Elsevier
T2  - Neuroscience Letters
T1  - Effects of low-intensity electrical stimulation and adipose derived stem cells transplantation on the time-domain analysis-based electromyographic signals in dogs with SCI
SP  - 38
EP  - 45
VL  - 696
DO  - 10.1016/j.neulet.2018.12.004
UR  - https://hdl.handle.net/21.15107/rcub_dais_4595
ER  - 

@article{
author = "Krueger, Eddy and Magri, L. M. S. and Botelho, A. S. and Bach, F. S. and Rebellato, C. L. K. and Fracaro, L. and Fragoso, F. Y. I. and Villanova, J. A. and Brofman, P. R. S. and Popović Maneski, Lana",
year = "2019",
abstract = "The application of low-intensity electrical stimulation (LIES) to neural tissue increases neurochemical factors responsible for regeneration as nerve growth factor. Stem cell (SC) therapy for patients with Spinal cord injury (SCI) promote some increase functional improvement.ObjectiveInvestigate the electromyographic response in paraplegic dogs undergoing LIES and SC transplantation.Methods27 dogs paraplegics with SCI were divided into three groups with different types of therapy. GADSC: two SC transplants (n = 9); GLIES: LIES (n = 8); GCOMB: two SC transplants and LIES (n = 10). Adipose derived mesenchymal stem cells (ADSCs) were transplanted by lumbar puncture in the amount of 1.2 × 106 cells/50 μL. Acupuncture needles positioned in the interspinous space were used for stimulation. The electrical stimulation was applied with a mean voltage ∼30 mV and four consecutive modulated frequencies (5 Hz, 10 Hz, 15 Hz and 20 Hz) within 5 min each. The patients motor performance was evaluated before (Pre) the procedure and after 30 (Post30) and 60 (Post60) days, from electromyography root mean square (EMGRMS) registered with subcutaneous electrodes in the vastus lateralis muscle, while the animals were in quadrupedal position.ResultsAll three groups showed a significant intra-group increase of EMGRMS (Pre vs. Post30 or Pre vs. Post60). However, there were no statistically significant differences between Post30 and Post60. The inter-group test (GADSC X GLIES X GCOMB) did not present significance when compared the instants Pre (p = 0.34), Post30 (p = 0.78) and Post60 (p = 0.64).ConclusionSome dogs recovered motor activity, expressed by the EMGRMS, in all groups, in pre vs. post (30 or 60 days) comparisons.",
publisher = "Elsevier",
journal = "Neuroscience Letters",
title = "Effects of low-intensity electrical stimulation and adipose derived stem cells transplantation on the time-domain analysis-based electromyographic signals in dogs with SCI",
pages = "38-45",
volume = "696",
doi = "10.1016/j.neulet.2018.12.004",
url = "https://hdl.handle.net/21.15107/rcub_dais_4595"
}

Krueger, E., Magri, L. M. S., Botelho, A. S., Bach, F. S., Rebellato, C. L. K., Fracaro, L., Fragoso, F. Y. I., Villanova, J. A., Brofman, P. R. S.,& Popović Maneski, L.. (2019). Effects of low-intensity electrical stimulation and adipose derived stem cells transplantation on the time-domain analysis-based electromyographic signals in dogs with SCI. in Neuroscience Letters
Elsevier., 696, 38-45.
https://doi.org/10.1016/j.neulet.2018.12.004
https://hdl.handle.net/21.15107/rcub_dais_4595

Krueger E, Magri LMS, Botelho AS, Bach FS, Rebellato CLK, Fracaro L, Fragoso FYI, Villanova JA, Brofman PRS, Popović Maneski L. Effects of low-intensity electrical stimulation and adipose derived stem cells transplantation on the time-domain analysis-based electromyographic signals in dogs with SCI. in Neuroscience Letters. 2019;696:38-45.
doi:10.1016/j.neulet.2018.12.004
https://hdl.handle.net/21.15107/rcub_dais_4595 .

Krueger, Eddy, Magri, L. M. S., Botelho, A. S., Bach, F. S., Rebellato, C. L. K., Fracaro, L., Fragoso, F. Y. I., Villanova, J. A., Brofman, P. R. S., Popović Maneski, Lana, "Effects of low-intensity electrical stimulation and adipose derived stem cells transplantation on the time-domain analysis-based electromyographic signals in dogs with SCI" in Neuroscience Letters, 696 (2019):38-45,
https://doi.org/10.1016/j.neulet.2018.12.004 .,
https://hdl.handle.net/21.15107/rcub_dais_4595 .