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2017 (3)
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Mitić, Vojislav

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81853588-7715-4cea-9063-42440fecafb2
  • Mitić, Vojislav (1)
  • Mitić, Vojislav V. (2)
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Author's Bibliography

Multistep Transformation Method for Discrete and Continuous Time Enzyme Kinetics

Lee, Bill; Gadow, Rainer; Mitić, Vojislav V.; Vosika, Zoran B.; Lazović, Goran; Mitić, Vojislav V.; Kocić, Ljubiša

(Paris : Atlantis Press, 2017)

TY  - CONF
AU  - Vosika, Zoran B.
AU  - Lazović, Goran
AU  - Mitić, Vojislav V.
AU  - Kocić, Ljubiša
PY  - 2017
UR  - http://dais.sanu.ac.rs/123456789/2359
AB  - In this paper we develop the new physical-mathematical time scale kinetic approach-model applied on organic and non-organic particles motion. Concretely, here, at first, this new research approach is based on enzyme particles dynamics results. At the beginning, a time scale is defined to be an arbitrary closed subset of the real numbers R, with the standard inherited topology. Mathematical examples of time scales include real numbers R, natural numbers N, integers Z, the Cantor set (i.e. fractals), and any finite union of closed intervals of R. Calculus on time scales (TSC) was established in 1988 by Stefan Hilger. TSC, by construction, is used to describe the complex process. This method may utilized for description of physical (classical mechanics), material (crystal growth kinetics, physical chemistry kinetics—for example, kinetics of barium-titanate synthesis), (bio)chemical or similar systems and represents major challenge for contemporary scientists. In this sense, the Michaelis-Menten (MM) mechanism is the one of the best known and simplest nonlinear biochemical network which deserves appropriate attention. Generally speaking, such processes may be described of discrete time scale. Reasonably it could be assumed that such a scenario is possible for MM mechanism. In this work, discrete time MM kinetics (dtMM) with time various step h, is investigated. Instead of the first derivative by time used first backward difference h. Physical basics for new time scale approach is a new statistical thermodynamics, natural generalization of Tsallis non-extensive or similar thermodynamics. A reliable new algorithm of novel difference transformation method, namely multi-step difference transformation method (MSDETM) for solving system of nonlinear ordinary difference equations is proposed. If h tends to zero, MSDETM transformed into multi-step differential transformation method (MSDTM). In the spirit of TSC, MSDETM describes analogously MSDTM.
PB  - Paris : Atlantis Press
C3  - Proceedings of the IV Advanced Ceramics and Applications Conference
T1  - Multistep Transformation Method for Discrete and Continuous Time Enzyme Kinetics
DO  - 10.2991/978-94-6239-213-7_22
ER  - 
@conference{
editor = "Lee, Bill, Gadow, Rainer, Mitić, Vojislav V.",
author = "Vosika, Zoran B. and Lazović, Goran and Mitić, Vojislav V. and Kocić, Ljubiša",
year = "2017",
url = "http://dais.sanu.ac.rs/123456789/2359",
abstract = "In this paper we develop the new physical-mathematical time scale kinetic approach-model applied on organic and non-organic particles motion. Concretely, here, at first, this new research approach is based on enzyme particles dynamics results. At the beginning, a time scale is defined to be an arbitrary closed subset of the real numbers R, with the standard inherited topology. Mathematical examples of time scales include real numbers R, natural numbers N, integers Z, the Cantor set (i.e. fractals), and any finite union of closed intervals of R. Calculus on time scales (TSC) was established in 1988 by Stefan Hilger. TSC, by construction, is used to describe the complex process. This method may utilized for description of physical (classical mechanics), material (crystal growth kinetics, physical chemistry kinetics—for example, kinetics of barium-titanate synthesis), (bio)chemical or similar systems and represents major challenge for contemporary scientists. In this sense, the Michaelis-Menten (MM) mechanism is the one of the best known and simplest nonlinear biochemical network which deserves appropriate attention. Generally speaking, such processes may be described of discrete time scale. Reasonably it could be assumed that such a scenario is possible for MM mechanism. In this work, discrete time MM kinetics (dtMM) with time various step h, is investigated. Instead of the first derivative by time used first backward difference h. Physical basics for new time scale approach is a new statistical thermodynamics, natural generalization of Tsallis non-extensive or similar thermodynamics. A reliable new algorithm of novel difference transformation method, namely multi-step difference transformation method (MSDETM) for solving system of nonlinear ordinary difference equations is proposed. If h tends to zero, MSDETM transformed into multi-step differential transformation method (MSDTM). In the spirit of TSC, MSDETM describes analogously MSDTM.",
publisher = "Paris : Atlantis Press",
journal = "Proceedings of the IV Advanced Ceramics and Applications Conference",
title = "Multistep Transformation Method for Discrete and Continuous Time Enzyme Kinetics",
doi = "10.2991/978-94-6239-213-7_22"
}
Lee, B., Gadow, R., Mitić, V. V., Vosika, Z. B., Lazović, G., Mitić, V. V.,& Kocić, L. (2017). Multistep Transformation Method for Discrete and Continuous Time Enzyme Kinetics.
Proceedings of the IV Advanced Ceramics and Applications ConferenceParis : Atlantis Press., null. 
https://doi.org/10.2991/978-94-6239-213-7_22
Lee B, Gadow R, Mitić VV, Vosika ZB, Lazović G, Mitić VV, Kocić L. Multistep Transformation Method for Discrete and Continuous Time Enzyme Kinetics. Proceedings of the IV Advanced Ceramics and Applications Conference. 2017;

Contemporary Dental Ceramics

Lee, Bill; Gadow, Rainer; Mitić, Vojislav V.; Pavlović, Vladimir B.; Vulićević, Z.; Pavlović, Vera P.

(Paris : Atlantis Press, 2017)

TY  - CONF
AU  - Pavlović, Vladimir B.
AU  - Vulićević, Z.
AU  - Pavlović, Vera P.
PY  - 2017
UR  - http://dais.sanu.ac.rs/123456789/2354
AB  - Dental ceramics were increasingly introduced to restorative dentistry at the beginning of the XX century as porcelain jacket crowns. However, their limited use in clinical practice was mainly associated to the mechanical shortcomings. In the early sixties porcelain-fused to-metal restorations were developed and for years have represented the “gold standard”, thanks to their good mechanical properties and to somewhat satisfactory esthetics. In the last thirty years, the growing demand for highly esthetic restorations has led to development of new all-ceramic materials and techniques. All-ceramic restorations combine esthetic veneering porcelains (consisting of a glass and a crystalline phase of fluoroapatite, aluminum oxide, or leucite) with strong ceramic cores, mainly made of lithium-disilicate, aluminum-oxide or zirconium-oxide. The most common complication is fracture that can initiate from several different sites on the surface, at interfaces, or within the material. While conventional methods of ceramic fabrication usually contain internal porosity, CAD/CAM technology ensures almost no internal defects. Such improvements in ceramic processing have allowed better structural reliability and greatly contributed to the success of all-ceramic systems. The aim of this study was to provide an overview on development of ceramic systems used in dentistry, their processing, including computer-aided design and computer-aided (CAD/CAM) technology, applications and future perspectives in this field.
PB  - Paris : Atlantis Press
C3  - Proceedings of the IV Advanced Ceramics and Applications Conference
T1  - Contemporary Dental Ceramics
SP  - 95
EP  - 119
DO  - 10.2991/978-94-6239-213-7_9
ER  - 
@conference{
editor = "Lee, Bill, Gadow, Rainer, Mitić, Vojislav V.",
author = "Pavlović, Vladimir B. and Vulićević, Z. and Pavlović, Vera P.",
year = "2017",
url = "http://dais.sanu.ac.rs/123456789/2354",
abstract = "Dental ceramics were increasingly introduced to restorative dentistry at the beginning of the XX century as porcelain jacket crowns. However, their limited use in clinical practice was mainly associated to the mechanical shortcomings. In the early sixties porcelain-fused to-metal restorations were developed and for years have represented the “gold standard”, thanks to their good mechanical properties and to somewhat satisfactory esthetics. In the last thirty years, the growing demand for highly esthetic restorations has led to development of new all-ceramic materials and techniques. All-ceramic restorations combine esthetic veneering porcelains (consisting of a glass and a crystalline phase of fluoroapatite, aluminum oxide, or leucite) with strong ceramic cores, mainly made of lithium-disilicate, aluminum-oxide or zirconium-oxide. The most common complication is fracture that can initiate from several different sites on the surface, at interfaces, or within the material. While conventional methods of ceramic fabrication usually contain internal porosity, CAD/CAM technology ensures almost no internal defects. Such improvements in ceramic processing have allowed better structural reliability and greatly contributed to the success of all-ceramic systems. The aim of this study was to provide an overview on development of ceramic systems used in dentistry, their processing, including computer-aided design and computer-aided (CAD/CAM) technology, applications and future perspectives in this field.",
publisher = "Paris : Atlantis Press",
journal = "Proceedings of the IV Advanced Ceramics and Applications Conference",
title = "Contemporary Dental Ceramics",
pages = "95-119",
doi = "10.2991/978-94-6239-213-7_9"
}
Lee, B., Gadow, R., Mitić, V. V., Pavlović, V. B., Vulićević, Z.,& Pavlović, V. P. (2017). Contemporary Dental Ceramics.
Proceedings of the IV Advanced Ceramics and Applications ConferenceParis : Atlantis Press., null, 95-119. 
https://doi.org/10.2991/978-94-6239-213-7_9
Lee B, Gadow R, Mitić VV, Pavlović VB, Vulićević Z, Pavlović VP. Contemporary Dental Ceramics. Proceedings of the IV Advanced Ceramics and Applications Conference. 2017;:95-119
1

The Influence of Nanomaterial Calcium Phosphate/poly-(dl-lactide-co-glycolide) on Proliferation and Adherence of HeLa Cells

Lee, Bill; Gadow, Rainer; Mitić, Vojislav; Najdanović, Jelena; Najman, Stevo; Stojanović, Sanja; Živković, Jelena M.; Ignjatović, Nenad; Uskoković, Dragan; Trajanović, Miroslav

(Paris : Atlantis Press, 2017)

TY  - CONF
AU  - Najdanović, Jelena
AU  - Najman, Stevo
AU  - Stojanović, Sanja
AU  - Živković, Jelena M.
AU  - Ignjatović, Nenad
AU  - Uskoković, Dragan
AU  - Trajanović, Miroslav
PY  - 2017
UR  - http://dais.sanu.ac.rs/123456789/2379
AB  - Nanomaterials are nowadays widely used in various fields of biomedicine. Before the application of biomaterials they have to be tested and fulfill some criteria. The first tests that should be performed after synthesis of some new nanomaterial with potential application in biomedical fields are biocompatibility tests. The aim of this study was to examine the influence of nanomaterial calcium phosphate/poly-(dl-lactide-co-glycolide) (CP/PLGA) on proliferation and adherence of HeLa cells in culture. For both proliferation and adherence examination, cells were treated with suspension of nanomaterial CP/PLGA at concentrations 5, 50 and 500 µg/mL, made in cell culture medium. There were four different types of treatment: (1) cells incubated with CP/PLGA for 3 days; (2) cells incubated with CP/PLGA for 6 days; (3) cells incubated first with CP/PLGA for 3 days and then for the next 3 days with medium and (4) cells incubated first with medium for 3 days and then for the next 3 days with CP/PLGA. Three days after incubation of HeLa cells with different concentrations of CP/PLGA nanoparticles’ suspension, the concentration of 5 µg/mL had mild inhibitory effect on proliferation. Increasing CP/PLGA concentration, there was stimulatory effect on cells’ proliferation. With prolonged incubation period, this dose dependence is lost. The highest adherence of HeLa cells was observed when cells were incubated with the highest examined concentration of CP/PLGA suspension, in both 3-day and 6-day incubation period. Based on the results obtained in our study, we can conclude that the effect of the suspension of nanomaterial CP/PLGA on proliferation and adherence of HeLa cells depends on the duration of incubation with the cells as well as the material concentration and type of the treatment.
PB  - Paris : Atlantis Press
C3  - Proceedings of the IV Advanced Ceramics and Applications Conference
T1  - The Influence of Nanomaterial Calcium Phosphate/poly-(dl-lactide-co-glycolide) on Proliferation and Adherence of HeLa Cells
SP  - 387
EP  - 400
DO  - 10.2991/978-94-6239-213-7_27
ER  - 
@conference{
editor = "Lee, Bill, Gadow, Rainer, Mitić, Vojislav",
author = "Najdanović, Jelena and Najman, Stevo and Stojanović, Sanja and Živković, Jelena M. and Ignjatović, Nenad and Uskoković, Dragan and Trajanović, Miroslav",
year = "2017",
url = "http://dais.sanu.ac.rs/123456789/2379",
abstract = "Nanomaterials are nowadays widely used in various fields of biomedicine. Before the application of biomaterials they have to be tested and fulfill some criteria. The first tests that should be performed after synthesis of some new nanomaterial with potential application in biomedical fields are biocompatibility tests. The aim of this study was to examine the influence of nanomaterial calcium phosphate/poly-(dl-lactide-co-glycolide) (CP/PLGA) on proliferation and adherence of HeLa cells in culture. For both proliferation and adherence examination, cells were treated with suspension of nanomaterial CP/PLGA at concentrations 5, 50 and 500 µg/mL, made in cell culture medium. There were four different types of treatment: (1) cells incubated with CP/PLGA for 3 days; (2) cells incubated with CP/PLGA for 6 days; (3) cells incubated first with CP/PLGA for 3 days and then for the next 3 days with medium and (4) cells incubated first with medium for 3 days and then for the next 3 days with CP/PLGA. Three days after incubation of HeLa cells with different concentrations of CP/PLGA nanoparticles’ suspension, the concentration of 5 µg/mL had mild inhibitory effect on proliferation. Increasing CP/PLGA concentration, there was stimulatory effect on cells’ proliferation. With prolonged incubation period, this dose dependence is lost. The highest adherence of HeLa cells was observed when cells were incubated with the highest examined concentration of CP/PLGA suspension, in both 3-day and 6-day incubation period. Based on the results obtained in our study, we can conclude that the effect of the suspension of nanomaterial CP/PLGA on proliferation and adherence of HeLa cells depends on the duration of incubation with the cells as well as the material concentration and type of the treatment.",
publisher = "Paris : Atlantis Press",
journal = "Proceedings of the IV Advanced Ceramics and Applications Conference",
title = "The Influence of Nanomaterial Calcium Phosphate/poly-(dl-lactide-co-glycolide) on Proliferation and Adherence of HeLa Cells",
pages = "387-400",
doi = "10.2991/978-94-6239-213-7_27"
}
Lee, B., Gadow, R., Mitić, V., Najdanović, J., Najman, S., Stojanović, S., Živković, J. M., Ignjatović, N., Uskoković, D.,& Trajanović, M. (2017). The Influence of Nanomaterial Calcium Phosphate/poly-(dl-lactide-co-glycolide) on Proliferation and Adherence of HeLa Cells.
Proceedings of the IV Advanced Ceramics and Applications ConferenceParis : Atlantis Press., null, 387-400. 
https://doi.org/10.2991/978-94-6239-213-7_27
Lee B, Gadow R, Mitić V, Najdanović J, Najman S, Stojanović S, Živković JM, Ignjatović N, Uskoković D, Trajanović M. The Influence of Nanomaterial Calcium Phosphate/poly-(dl-lactide-co-glycolide) on Proliferation and Adherence of HeLa Cells. Proceedings of the IV Advanced Ceramics and Applications Conference. 2017;:387-400
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